Two sample MR report
ELP5_T Proliferating against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.1338649 | 0.2029352 | 0.5386498 |
| Weighted median | 7 | -0.0861068 | 0.0227976 | 0.0001587 |
| Inverse variance weighted | 7 | -0.0992621 | 0.0183239 | 0.0000001 |
| Simple mode | 7 | -0.0835618 | 0.0324727 | 0.0421479 |
| Weighted mode | 7 | -0.0825980 | 0.0303352 | 0.0345122 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.8559682 | 5 | 0.9733270 |
| Inverse variance weighted | 2.1865019 | 6 | 0.9017717 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1576042 | 0.1366328 | 0.3008517 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001783 | 0 | TRUE | 0.2094574 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
